Music and stress in children during general anesthesia and surgery


Recently I came across this very interesting study and thought my readers would want to know about it.  Music during surgery can help with ALL populations!  This was done by  Helena Bogopolsky.


The research I am about to present today has taken three years. Its goal was to reduce physiological and emotional stress in patients undergoing general anesthesia. The research questions were:

Is there audio perception when under anesthesia?

Can we find a parameter that would measure the physiological and biochemical effect of music under anesthesia?

As a resident music therapist in the children’s surgery department of the Medical Center in Jerusalem, I witnessed the positive effects of music on the emotional state of pre- and post-operative children. These encounters gave me the incentive to research the effects music might have during the process of the surgery itself.

I speculated that playing music to children undergoing general anesthesia would help to reduce their psychological and physiological stress levels.

Let us begin with my first question and see what we know about hearing during general anesthesia:

Hearing and Memory Under General Anesthesia


Lately, research has shown that people are able to hear and report what they heard while under general anesthesia (McCarron and Bonny, 1984).

How would you feel, if you were anesthetized during surgery and heard the following?

Just a moment! I don’t like the patient’s color. Much too blue.

Her lips are very blue. I’m going to give a little more oxygen. . . .

There, that’s better now. You can carry on with the operation.

(Levinson, 1965:544)

Patients are not EXPECTED to be aware of events during anesthesia, and they are not EXPECTED to have any post-surgical memories of events that happened during anesthesia. However, despite these expectations, research (Levinson 1965, Gurman 2000) has shown that in many cases high level auditory processing (as is necessary for music perception) still exists for at least some patients undergoing general anesthesia. In addition, research shows that even if the patients cannot recall exactly what happened in the Operating Room, evidence of their experiences comes up in implicit memory tasks (Gurman 2000).

The implications of such reports are serious indeed. Patients may be at risk of psychological trauma that they not even aware of, or know the source of. In fact, research shows that of those patients who are aware during general anesthesia, 80% show symptoms compatible with Post Traumatic Stress Syndrome (Cundy and Dasey, 1996: 143). So, if nothing else, simply wearing headphones and being exposed to music rather than to stressful comments during the operation could have beneficial results.

However, we hypothesize that the administration of music during anesthesia has much deeper effects. These effects are related to music’s ability to influence physical and psychological states.

Review of Literature


Discussions about the influence of music on depression and pain have been around since at least the beginning of the 1800’s. Some stories even go back to biblical times. Technological means for measuring results have only come recently. But we still do not know exactly what effect music has on the human body.

So What Do We Know Today?

We know the following effects which music has on the human body:

Physiological and Psychological Aspects:

First of all, we definitely know that music affects the limbic system which regulates deep emotions and many involuntary physical operations and reactions (pulse & blood pressure)

Second, music may alter pain perception and pain sensation.

Third, Music also assists in reducing stress levels:

In the light of the effects mentioned above, it is reasonable to assume that music can provide a significant contribution in reducing stress during anesthesia.

Effects of Music on Patients Under Anesthesia:

A number of studies have shown positive effects of music on patients undergoing general anesthesia. However, there are still many questions unresolved.

Firstly, what are the tests or diagnostics available to measure emotional stress directly?

Secondly, would music have the same positive effects on children undergoing general anesthesia?

Stress caused by Hospitalization

As we know, hospitalization can be a traumatic experience. The experience of being cut off from home, surgery and treatment, creates a stressful reaction (Sekeles, 1996).

As mentioned before, surgery and anesthesia are physically stressful and can be measured scientifically. This contrasts with emotional stress, which is more difficult to define and to measure. In addition, doctors believe that the patients’ emotional state is very important for their recovery.

How to measure emotional stress?

One of the first difficulties I faced was how to measure the emotional stress in children. Since only measurable results are valid, finding a measure for emotional stress was quite important. Such a parameter needs to be standardized, which is not always easy.

We decided to measure the level of Cortisol known as “the stress hormone”.

Although stress isn’t the only reason that cortisol is secreted into the bloodstream, it has been termed “the stress hormone” because it’s also secreted in higher levels during the body’s `fight or flight’ response to stress, and is responsible for several stress-related changes in the body. (Elizabeth Scott)

Since we could not use blood tests for this research because of the Helsinki committee’s limitations on intrusive procedures, we opted for measuring Cortisol levels in saliva.

Research Design


In order to achieve standardization, my research concentrates on relatively simple eye operations. I investigate the effects of music on patients undergoing general anesthesia, for eye surgery, by comparing both the quality of the post-operative behavior and the biochemical levels of Cortisol – the stress hormone.

I begin by meeting with children ages 6 to18 in the preoperative preparation program. I let them know that they have the option of listening to music during the operation. If the child shows interest, I obtain written permission from the child, their parents and the medical staff. The child then brings their personal choice of music which was pre-selected in an interview before the operation.

During the operation, I supply the child with a set of specially designed earphones that do not interfere with the surgery. The music is turned on and adjusted to a level that does not exceed 65-70 dB (typical for experiments in music cognition).

In order to measure the effects of the music and to measure stress levels before, during and after the time of the operation, the saliva test is taken 3 times:

First, one day before the operation.

Second, immediately before anesthesia

Third, upon awakening from anesthesia after the operation.

Besides the saliva test, we used two additional and complementary scales in order to assess the patient’s state.

The first scale was the 4-point Watcha Agitation Scale, which was applied when the child awoke from the anesthetic by the attending nurse, who reported the child’s agitation level to the researcher.

As you can see on the 4-point Watcha Agitation Scale:

TABLE 1. 4-Point Agitation Scale – Watcha Relaxed


Crying but consolable


Crying inconsolably




The second scale was the Oucher Visual Pain Scale, which was also applied on awakening from the anesthesia

FIGURE 1. Oucher Visual Pain-Scale


Subject Demographics

The research population included children between the ages of 6-18. This age range was selected so as to enable me to communicate with them freely. The children came from 4 different cultural backgrounds:

Secular Jews

Secular Arabs

Religious Jews

Religious Arabs

The patients’ languages included Hebrew, Arabic, English and Russian.

In the case of Arabic speaking children, I invited the parents to assist in translation. In the case of Hebrew, English and Russian speaking children, I personally communicated with the children myself.

How was the music chosen?

My first thought was to choose relaxing music, for example ocean waves or classical pieces. In the end, however, I decided to let the child bring his or her favorite music because it gives them a sense of comfort and security.

By playing the child’s favorite music during the operation, the music served as a “transitional object” (Winnicott, 1971), which helped to overcome unpleasant feelings and loneliness.

What type of music did the children want?

The interesting thing about their choice of music was its intensive tempo and rhythm. I will now play some examples of their choices.

As we have heard, their choice of music is far from “lullaby”, but does contain some common features:

It is familiar

It is music they have at home

There is a singer

Fast rhythm and tempo



As the next table shows, the results, despite not being statistically conclusive, show that the music group’s awakening was much more pleasant. We compared several categories as we see from the table

The most significant effect, 21 percent, appears in the comparative study of short operations (less than 65 minutes).

TABLE 2. Comparative Results of Quality of Awakening between Control Group and Music Group Description



Study of the effect of music therapy on quality of awakening

The result shows an effect (11.9 %) of provided treatment on patients’ awakeness. (student t-test, 0.1664)

Study of the effect of music therapy on quality of awakening in Jewish patients

The result shows an effect (15.3%) of the therapy on patients’ awakeness for Jewish patients. (student t-test, 0.129). It is also important to note that there is no difference between the awakeness quality values for Jewish and general patients

Study of the effect of music therapy on quality of awakening after operation for Strabismus correction.

The result shows an effect (14.3%) of the therapy on patients’ awakeness after Strabismus correction operation (student t-test, 0.187).

Study of the effect of music therapy on quality of awakening after short time (less 65 min) operations.

The result shows a significant effect (21%) of the therapy on patients’ awakeness after short time operations (student t-test, 0.081).

Study of the effect of music therapy on quality of awakening for both genders

The result shows an effect of the therapy on patients’ awakeness for boys (15.6%) and girls (13.6%) (student t-tests, 0.155 and 0.213, comparatively).

It is also interesting to mention that the studied girls show better post-operative awakeness capability in both, control (17.3%, t-test 0.205) and treated (15.4%, t-test 0.17), groups.

FIGURE 2. Salivary cortisol test


This table shows the results of the cortisol test. The first time checkpoint was one day before surgery; the second checkpoint was one hour before surgery, and the third checkpoint was one hour after surgery. As we can see, the results are not statistically conclusive, but they do show a clear tendency in favor of the music group.



Initially, I thought that measuring the effects of music would be simple. That I would play music to patients, measure their stress levels, and immediately see the benefits that music gave. It turned out that the process was much more complicated. Factors such as the depth of anesthesia, levels of emotional stress, standardizing, and measuring results have all added to the complexity of the experiment. Apart from that, the experiment lacked the optimal infrastructure necessary for a clinical study in the field. And in addition, we discovered during our work that testing for cortisol is a non-routine test and has no acknowledged base line. Nor did we take into account the fact that cortisol levels fluctuate during the day. They can be high in the morning and lower later on, and the cortisol tests we carried out were on children whose surgery was scheduled at different times of the day.

It should be noted that, for technical reasons, the number of subjects tested for cortisol levels was limited, which should be taken into account in future experiments and the number increased. We also felt that objective tests of cortisol and awakening quality should be complemented by subjective psychological tests such as questionnaires. We did not use questionnaires in this study, but in conversations a week after surgery the importance of providing emotional support by means of music for children and their parents was clear.

It is certainly clear from the above that future research should include the use of questionnaires which give insight into subjective experiences and complement the objective use of cortisol.

Finally, I should say that the most important thing my research has shown me is that despite the lack of statistically conclusive results in the physiological and biochemical test I stay convinced more than ever, that music is an effective means for lowering stress in children during general anesthesia and surgery.


References of this conference paper can be obtained by the author

This article can be cited as:

Bogopolsky, H. (2007) Music and stress in children during general anesthesia and surgery. Music Therapy Today Vol.VIII (3) December. available at


What investors are saying about Surgical Serenity Headphones


I met with all of my investors this past week and they all have really dynamite ideas for ways to move the Surgical Serenity Headphones into the mainstream.  All of these men are extremely successful business men who have bought and sold hundreds of businesses.  One of the suggestions was to make contact NOW with major manufacturers of medical devices.  Through the program LinkedIn I have been able to do that!  The world of the internet never ceases to amaze me with all the possibilities for networking with people.
A different investor simply gave me testimonial after testimonial.  He has had numerous surgeries in the past and hates pain he said (among other things) “Dr. Cash, if you can prevent me from feeling as much pain, requiring so much anesthesia and help me to relax and calm down with your special music, then please send me some immediately!”  He said I could even give his name…Bill Ferko.
It seems that all the investors are pretty excited about the potential of these headphones to be accepted by hospitals, surgeons and anesthesiologists around the world.  It seems logical to me because calming your mind and body before surgery with music and stabilizing your heart rate and breathing during surgery with steady, instrumental music can only improve the entire procedure, increase safety be decreasing the amount of anesthesia needed and allow the patient to recover faster, be discharged sooner and incur few expenses.
I fully intend to have a charity arm of the organization to provide headphones to those who can’t afford them, but ideally I’d like to gather enough research documenting the benefits of the headphones so that insurance companies will not only cover them, but require them. 

I’d love to hear your ideas and suggestions about all the above.  Thanks!


Talks with Mayo Clinic have begun!


HeadphonesHaving Surgical Serenity Solutions inside the Mayo Clinic has always been a dream of mine!  Let me start out my saying that this is not going to be a quick happening but at least it has begun!  I talked with my second “official” person at Mayo Clinic today about the possibility of getting my headphones in use there.  They are already definitely in favor of people using music before, during and after their surgery but are not aware of my self-contained, wireless, pre-programmed headphones.

The Surgery/Anesthesia staff at Mayo Clinic KNOW that music is a powerful adjunct to anesthesia and that many patients are exceptionally sensitive to even the mildest anesthesia.  The doctors that I’ve talked with there have said that from pre-op through post-op and even at home afterwards, they would love to have a way to provide the ideal music  to every patient.  In the past, patients have been allowed to bring in whatever tapes or CDs they wanted and the hospital found a number of different ways to put the music in a rubber glove, or a surgical cap, so as not to spread germs into the “sterile space.”  Of course they see the benefits of each patient having their own hospital-issued, pre-programmed, cordless headphones!

I’m awaiting calls now from two people who might be in a position to make a decision or at least a decision to gather more information.

In the meantime, if you have not seen the latest info at, please go there NOW and find out how beneficial and even potentially life-saving, music with surgery can be!

Will continue to keep you posted!


Another first-person account of music during surgery!


Jane Zellmer was anxious about her second knee replacement surgery.

The first surgery on her left knee was done under general anesthesia. She said she doesn’t do well under general anesthesia, and she had a difficult time waking up and was nauseous the first time.

This time the 54-year-old Ettrick, Wis., woman wanted spinal anesthesia, which would allow her to be conscious while numbing her right knee.

Zellmer also chose music to help with her anxiety and make her relax. Mike Jacobson, a nurse anesthetist at Franciscan Skemp, had a library of music from which she could pick. She chose her favorite music, country, and a favorite artist, George Strait.

With her headphones on, she listened to Strait’s music during surgery.

“It was very calming listening to the music, and I was comfortable,” Zellmer said. “I was nervous about the spinal anesthesia, but the music helped me relax.

“I felt like I was lying in the sun with headphones on,” she said. “Music did its thing, and it was a place to go, something to escape into. The spinal anesthesia and music worked real well together.”

For several years, a number of hospitals, including Franciscan Skemp and Gundersen Lutheran, have offered music to patients during surgery. Zellmer heard about the use of music through a friend who listened to music during surgery at Gundersen Lutheran.

More and more hospitals are using music for patients because research is showing it helps reduce moderate pain and anxiety, and it might result in less sedation and faster recovery.

A Yale University showed patients listening to music required much less sedation during surgery. Another study showed listening to music helps minimize the rise in blood pressure associated with surgery. Researchers say the best results are likely to come from people being able to listen to the music of their own choice rather than being given music thought to be soothing.

For many years, surgery rooms have been filled with the sound of music selected by and for surgeons.

“Music often helps surgeons relax, and some like it for background music,” Jacobson said. “One surgeon likes very loud rock ’n’ roll.

“Patients have their own music option, but it’s the surgeon’s choice in the room,” he said. “I’ve never been asked what I want to hear, but I think whatever music helps the surgeon is a good choice.”

Dr. Mark Connelly, a Gundersen Lutheran facial plastic surgeon, has played music in his operating room for more than 25 years. He has a CD of Broadway show tunes, pop, country and classical music.

“The music is soothing, and it helps me relax,” Connelly said.

“Occasionally, the staff will sing along to ‘Stand By Your Man,’” he said. “Surgeons get to choose the music, but it’s nice when the operating group likes it.”

Jacobson is one of the DJs at Franciscan Skemp. He is in charge of a cart of CDs from which patients can choose, or they can bring in their own CDs.

“Some people like country, some like classical and some New Age, but more patients like soothing music,” Jacobson said. “Music does help calm the patient.”

Dr. Marisa Baorto, a Franciscan Skemp anesthesiologist, said music is used in conjunction with “conscious sedation,” such as spinal and regional anesthesia, for surgeries such as foot, carpal tunnel, knee replacement and breast biopsies.

Baorto said some pregnant women bring in their own music to listen to during labor.

“A lot of patients enjoy the music, and then they don’t have to hear what’s going on in surgery,” Baorto said. “Music helps them phase out and get less sedation.”

Jacobson said he can tell the difference in patients who enjoy the music.

“We can tell the patient is more calm,” Jacobson said. “I don’t think it is fluff. There are benefits to the patient, even some benefits during general anesthesia.”